This research reports scalable approaches to flexible bio-compatible electronic systems, where thin microscale device components integrate onto flexible polymer substrates in interconnected arrays to provide multimodal, high-performance operational capabilities as intimately coupled bio-interfaces.

The material options and engineering schemes summarized in this research serve as foundations for diverse, heterogeneously integrated systems.

Detailed in vitro studies suggest the ability of these systems to provide sophisticated electronic and optoelectronic functions with a stable, biologically safe operation for many decades. The results define concepts and technological approaches with widespread utility in the field of bioelectronics.